Quoting: Cunning Plan
I use Time Machine on the Mac with a separate 1TB drive. TM is capable of restoring the whole system from the 1TB drive onto a new disk.
(http://www.mkb.cc/forum/smileys/plusone.gif)
Took me a little while to getting round to it, but now it's up and running, I just leave it plugged in, every now and then it spins up and makes a backup. Love the simplicity of it.
Also use Vault in Aperture to back up all my projects.