well.... The Amp does have speaker level inputs so it will run on a standard head unit that doesn't have RCA preOuts, pretty rare on an amp now.
the amp is a 2 channel output, I bought it to run the pair of 6x9s, it will however run 4 speakers, they will have balance control L/R but no fader F/R. Or, I guess you could hook it up with the fronts on one channel and the rears on the other, i mean, how often do you really use balance control! I know I use the fader a fair bit so that's probably a more sensible way of doing it seein as the rears/fronts are different size speakers
According to the manual it can be hooked up like this:
Now, it will do it but it will drop the amp in to 2 Ohms which will double the RMS wattage, not ideal really but it will work
TBH I would use this to drive the rear 6x9s and use the stock head unit to drive the fronts. That's the ideal way imo.